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FIGURE 7 Persistent accumulation of ROS induces lipid peroxidation in keratinocyte membranes and structural proteins, resulting in impaired barrier function and increased TEWL (Yang et al., 2022

Clinical trials have shown that a daily 25mg Wegovy pill can result in an average 16.6% body weight reduction after 64 weeks compared to 2.7% with a placebo

Individual response variation means some users find benefit at lower doses while others require higher amounts

Bidirectional interactions between nutrients and the gut microbiota: most studies focus on the unidirectional effect of nutrients regulating the microbiota [e.g., vitamin D increasing the abundance of Roseburia (103)]